The evidence behind the guides

Sources library

Browse by topic or search for a study, author or question. Open evidence notes to see what a source can—and cannot—tell us.

TopicCollection

Sources for Sepsis-prediction reliability

1 source

Guide citations are still under editorial review.

JAMA Network Open 2026 Prospective validation

Multicenter Prospective Validation of an Updated Proprietary Sepsis Prediction Model (original source, new tab)

Four health systems evaluating Epic Sepsis Model version 2; improved discrimination alongside institutional variation and alert burden.

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